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LATS2 is De-methylated and Overexpressed in Nasopharyngeal Carcinoma and Predicts Poor Prognosis

BACKGROUND: LATS2, which encodes a novel serine/threonine kinase, is known to be important in centrosome duplication and in the maintenance of genomic stability. Recently, a potential role for LATS2 in cancer has been reported. In breast cancer and acute lymphoblastic leukemia (ALL), LATS2 mRNA is d...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Hu, Chun-Fang, Chen, Jing, Yan, Li-Xu, Zeng, Yi-Xin, Shao, Jian-Yong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958949/
https://www.ncbi.nlm.nih.gov/pubmed/20932276
http://dx.doi.org/10.1186/1471-2407-10-538