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Over-expression of HO-1 on mesenchymal stem cells promotes angiogenesis and improves myocardial function in infarcted myocardium

Heme oxygenase-1 (HO-1) is a stress-inducible enzyme with diverse cytoprotective effects, and reported to have an important role in angiogenesis recently. Here we investigated whether HO-1 transduced by mesenchymal stem cells (MSCs) can induce angiogenic effects in infarcted myocardium. HO-1 was tra...

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Detalles Bibliográficos
Autores principales: Zeng, Bin, Lin, Guosheng, Ren, Xiaofeng, Zhang, Yan, Chen, Honglei
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959016/
https://www.ncbi.nlm.nih.gov/pubmed/20925964
http://dx.doi.org/10.1186/1423-0127-17-80