Expression of inwardly rectifying potassium channels by an inducible adenoviral vector reduced the neuronal hyperexcitability and hyperalgesia produced by chronic compression of the spinal ganglion

BACKGROUND: A chronic compressed dorsal root ganglion (CCD) in rat produces pain behavior and an enhanced excitability of neurons within the compressed ganglion. Kir2.1 is an inwardly rectifying potassium channel that acts to stabilize the resting potential of certain cell types. We hypothesized tha...

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Detalles Bibliográficos
Autores principales: Ma, Chao, Rosenzweig, Jason, Zhang, Pu, Johns, David C, LaMotte, Robert H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959023/
https://www.ncbi.nlm.nih.gov/pubmed/20923570
http://dx.doi.org/10.1186/1744-8069-6-65

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959023/
https://www.ncbi.nlm.nih.gov/pubmed/20923570
http://dx.doi.org/10.1186/1744-8069-6-65

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