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Non-viral siRNA delivery into the mouse retina in vivo

BACKGROUND: Gene silencing in the retina using RNA interference could open broad possibilities for functional studies of genes in vivo and for therapeutic interventions in eye disorders. Therefore, there is a considerable demand for protocols to deliver siRNA into the vertebrate retina. In this work...

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Detalles Bibliográficos
Autores principales: Turchinovich, Andrey, Zoidl, Georg, Dermietzel, Rolf
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959040/
https://www.ncbi.nlm.nih.gov/pubmed/20920307
http://dx.doi.org/10.1186/1471-2415-10-25