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Discovering joint associations between disease and gene pairs with a novel similarity test

BACKGROUND: Genes in a functional pathway can have complex interactions. A gene might activate or suppress another gene, so it is of interest to test joint associations of gene pairs. To simultaneously detect the joint association between disease and two genes (or two chromosomal regions), we propos...

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Detalles Bibliográficos
Autores principales: Lin, Wan-Yu, Lee, Wen-Chung
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959050/
https://www.ncbi.nlm.nih.gov/pubmed/20920333
http://dx.doi.org/10.1186/1471-2156-11-86