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Discovering joint associations between disease and gene pairs with a novel similarity test
BACKGROUND: Genes in a functional pathway can have complex interactions. A gene might activate or suppress another gene, so it is of interest to test joint associations of gene pairs. To simultaneously detect the joint association between disease and two genes (or two chromosomal regions), we propos...
Autores principales: | Lin, Wan-Yu, Lee, Wen-Chung |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959050/ https://www.ncbi.nlm.nih.gov/pubmed/20920333 http://dx.doi.org/10.1186/1471-2156-11-86 |
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