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Methyl [hydr­oxy(phen­yl)phosphono­meth­yl]phospho­nate methanol solvate

The title compound, C(8)H(12)O(7)P(2)·CH(4)O, is a monoesterified bis­phospho­nate (or 1-hydroxy­methyl­ene-1,1-bis­phospho­nic acid). These synthetic compounds are widely used in medicine to inhibit bone resorption in diseases like osteoporosis, and are characterized by a stable P—C—P group and are...

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Detalles Bibliográficos
Autores principales: Dupont, Nathalie, Retailleau, Pascal, Migianu-Griffoni, Evelyne, Barbey, Carole
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959469/
https://www.ncbi.nlm.nih.gov/pubmed/21201089
http://dx.doi.org/10.1107/S160053680802285X