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4-Des­oxy-4β-[(5-meth­oxy-1H-indol-3-yl)oxalylamino]podophyllotoxin methanol solvate

The main mol­ecule of the title solvate, C(33)H(30)N(2)O(10)·CH(3)OH, is a new anti­tumor agent, which shows cytotoxicity against MDR cancer cell lines. It has been synthesized by coupling 4β-amino­podophyllotoxin with (5-meth­oxy-1H-indol-3-yl)glyoxyl chloride and structurally characterized. There...

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Detalles Bibliográficos
Autores principales: Feng, Min, Zhao, Ming, Zhang, Jingze, Yang, Zaixin, Chen, Hong
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959988/
https://www.ncbi.nlm.nih.gov/pubmed/21581314
http://dx.doi.org/10.1107/S1600536808035319