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4-Desoxy-4β-[(5-methoxy-1H-indol-3-yl)oxalylamino]podophyllotoxin methanol solvate
The main molecule of the title solvate, C(33)H(30)N(2)O(10)·CH(3)OH, is a new antitumor agent, which shows cytotoxicity against MDR cancer cell lines. It has been synthesized by coupling 4β-aminopodophyllotoxin with (5-methoxy-1H-indol-3-yl)glyoxyl chloride and structurally characterized. There...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2959988/ https://www.ncbi.nlm.nih.gov/pubmed/21581314 http://dx.doi.org/10.1107/S1600536808035319 |