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Ethyl 6-ethoxy­carbonyl­methyl-4-(2-hydroxy­phen­yl)-2-oxo-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate

The title compound, C(17)H(20)N(2)O(6), belongs to the monastrol-type of anti­cancer agents and was selected for crystal structure determination in order to confirm its mol­ecular structure and explore some aspects of its structure–activity relationships. The central tetra­hydro­pyrimidine ring has...

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Detalles Bibliográficos
Autores principales: Kettmann, Viktor, Světlík, Jan, Veizerová, Lucia
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961528/
https://www.ncbi.nlm.nih.gov/pubmed/21202607
http://dx.doi.org/10.1107/S1600536808012683