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Plasmid DNA delivery into MDA-MB-453 cells mediated by recombinant Her-NLS fusion protein

A major rate-limiting step in nonviral gene delivery is the entry of nucleic acids across various membrane barriers and eventually into the nucleus where it must be transcribed. Cell-penetrating peptides and proteins are employed to generate formulations that overcome these challenges to facilitate...

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Detalles Bibliográficos
Autores principales: Jeyarajan, Sivakumar, Xavier, Jennifer, Rao, N Madhusudhana, Gopal, Vijaya
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962268/
https://www.ncbi.nlm.nih.gov/pubmed/21042418
http://dx.doi.org/10.2147/IJN.S13040