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Profile of temsirolimus in the treatment of advanced renal cell carcinoma

Temsirolimus is a potent inhibtor of the mammalian target of rapamycin (mTOR). In various clinical trials temsirolimus has shown an overall survival benefit for patients with metastatic renal cell carcinoma (mRCC). Thus it is approved for first-line therapy in high-risk mRCC patients. We discuss the...

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Detalles Bibliográficos
Autores principales: Staehler, Michael, Haseke, Nicolas, Khoder, Wael, Stief, Christian G
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962305/
https://www.ncbi.nlm.nih.gov/pubmed/21049085