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Ras Homolog Enriched in Brain (Rheb) Enhances Apoptotic Signaling

Rheb is a homolog of Ras GTPase that regulates cell growth, proliferation, and regeneration via mammalian target of rapamycin (mTOR). Because of the well established potential of activated Ras to promote survival, we sought to investigate the ability of Rheb signaling to phenocopy Ras. We found that...

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Detalles Bibliográficos
Autores principales: Karassek, Sascha, Berghaus, Carsten, Schwarten, Melanie, Goemans, Christoph G., Ohse, Nadine, Kock, Gerd, Jockers, Katharina, Neumann, Sebastian, Gottfried, Sebastian, Herrmann, Christian, Heumann, Rolf, Stoll, Raphael
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962498/
https://www.ncbi.nlm.nih.gov/pubmed/20685651
http://dx.doi.org/10.1074/jbc.M109.095968