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Ras Homolog Enriched in Brain (Rheb) Enhances Apoptotic Signaling
Rheb is a homolog of Ras GTPase that regulates cell growth, proliferation, and regeneration via mammalian target of rapamycin (mTOR). Because of the well established potential of activated Ras to promote survival, we sought to investigate the ability of Rheb signaling to phenocopy Ras. We found that...
Autores principales: | Karassek, Sascha, Berghaus, Carsten, Schwarten, Melanie, Goemans, Christoph G., Ohse, Nadine, Kock, Gerd, Jockers, Katharina, Neumann, Sebastian, Gottfried, Sebastian, Herrmann, Christian, Heumann, Rolf, Stoll, Raphael |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962498/ https://www.ncbi.nlm.nih.gov/pubmed/20685651 http://dx.doi.org/10.1074/jbc.M109.095968 |
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