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Notch Signaling Activation Suppresses v-Src-Induced Transformation of Neural Cells by Restoring TGF-β-Mediated Differentiation

BACKGROUND: We have been investigating how interruption of differentiation contributes to the oncogenic process and the possibility to reverse the transformed phenotype by restoring differentiation. In a previous report, we correlated the capacity of intracellular Notch (ICN) to suppress v-Src-media...

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Detalles Bibliográficos
Autores principales: Amarir, Samira, Marx, Maria, Calothy, Georges
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962636/
https://www.ncbi.nlm.nih.gov/pubmed/21042581
http://dx.doi.org/10.1371/journal.pone.0013572