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ApoE−/− PGC-1α−/− Mice Display Reduced IL-18 Levels and Do Not Develop Enhanced Atherosclerosis

BACKGROUND: Atherosclerosis is a chronic inflammatory disease that evolves from the interaction of activated endothelial cells, macrophages, lymphocytes and modified lipoproteins (LDLs). In the last years many molecules with crucial metabolic functions have been shown to prevent important steps in t...

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Detalles Bibliográficos
Autores principales: Stein, Sokrates, Lohmann, Christine, Handschin, Christoph, Stenfeldt, Elin, Borén, Jan, Lüscher, Thomas F., Matter, Christian M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962638/
https://www.ncbi.nlm.nih.gov/pubmed/21042583
http://dx.doi.org/10.1371/journal.pone.0013539