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ApoE−/− PGC-1α−/− Mice Display Reduced IL-18 Levels and Do Not Develop Enhanced Atherosclerosis
BACKGROUND: Atherosclerosis is a chronic inflammatory disease that evolves from the interaction of activated endothelial cells, macrophages, lymphocytes and modified lipoproteins (LDLs). In the last years many molecules with crucial metabolic functions have been shown to prevent important steps in t...
Autores principales: | Stein, Sokrates, Lohmann, Christine, Handschin, Christoph, Stenfeldt, Elin, Borén, Jan, Lüscher, Thomas F., Matter, Christian M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962638/ https://www.ncbi.nlm.nih.gov/pubmed/21042583 http://dx.doi.org/10.1371/journal.pone.0013539 |
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