Enhancement of cell-specific transgene expression from a Tet-Off regulatory system using a transcriptional amplification strategy in the rat brain

BACKGROUND: The Tet-Off system uses a tetracycline-controlled transactivator protein (tTA) and a tetracycline-responsive promoter element (TRE) to regulate expression of a target gene. This system can be used to achieve regulatable transgene expression in specific cell types by employing a cell-spec...

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Detalles Bibliográficos
Autores principales: Liu, Beihui, Wang, Shu, Brenner, Michael, Paton, Julian FR, Kasparov, Sergey
Formato: Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd. 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962808/
https://www.ncbi.nlm.nih.gov/pubmed/18324737
http://dx.doi.org/10.1002/jgm.1178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962808/
https://www.ncbi.nlm.nih.gov/pubmed/18324737
http://dx.doi.org/10.1002/jgm.1178

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