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An Evaluation of Statistical Approaches to Rare Variant Analysis in Genetic Association Studies

Genome-wide association (GWA) studies have proved to be extremely successful in identifying novel common polymorphisms contributing effects to the genetic component underlying complex traits. Nevertheless, one source of, as yet, undiscovered genetic determinants of complex traits are those mediated...

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Detalles Bibliográficos
Autores principales: Morris, Andrew P, Zeggini, Eleftheria
Formato: Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962811/
https://www.ncbi.nlm.nih.gov/pubmed/19810025
http://dx.doi.org/10.1002/gepi.20450