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Gene Expression Changes Induced by PPAR Gamma Agonists in Animal and Human Liver

Thiazolidinediones are a class of Peroxisome Proliferator Activated Receptor γ (PPARγ) agonists that reduce insulin resistance in type 2 diabetic patients. Although no detectable hepatic toxicity has been evidenced in animal studies during preclinical trials, these molecules have nevertheless induce...

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Detalles Bibliográficos
Autores principales: Rogue, Alexandra, Spire, Catherine, Brun, Manuel, Claude, Nancy, Guillouzo, André
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963138/
https://www.ncbi.nlm.nih.gov/pubmed/20981297
http://dx.doi.org/10.1155/2010/325183