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Gene Expression Changes Induced by PPAR Gamma Agonists in Animal and Human Liver
Thiazolidinediones are a class of Peroxisome Proliferator Activated Receptor γ (PPARγ) agonists that reduce insulin resistance in type 2 diabetic patients. Although no detectable hepatic toxicity has been evidenced in animal studies during preclinical trials, these molecules have nevertheless induce...
Autores principales: | Rogue, Alexandra, Spire, Catherine, Brun, Manuel, Claude, Nancy, Guillouzo, André |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963138/ https://www.ncbi.nlm.nih.gov/pubmed/20981297 http://dx.doi.org/10.1155/2010/325183 |
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