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Toll-Like Receptor Signaling Pathways—Therapeutic Opportunities
Toll-like receptors (TLRs) are transmembrane proteins acting mainly as sensors of microbial components. Triggering TLRs results in increased expression of multiple inflammatory genes, which then play a protective role against infection. However, aberrant activation of TLR signaling has a significant...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963142/ https://www.ncbi.nlm.nih.gov/pubmed/20981241 http://dx.doi.org/10.1155/2010/781235 |