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Leptin Gene Epigenetic Adaptation to Impaired Glucose Metabolism During Pregnancy

OBJECTIVE: To verify whether the leptin gene epigenetic (DNA methylation) profile is altered in the offspring of mothers with gestational impaired glucose tolerance (IGT). RESEARCH DESIGN AND METHODS: Placental tissues and maternal and cord blood samples were obtained from 48 women at term including...

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Detalles Bibliográficos
Autores principales: Bouchard, Luigi, Thibault, Stéphanie, Guay, Simon-Pierre, Santure, Marta, Monpetit, Alexandre, St-Pierre, Julie, Perron, Patrice, Brisson, Diane
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963508/
https://www.ncbi.nlm.nih.gov/pubmed/20724651
http://dx.doi.org/10.2337/dc10-1024