Neutralization of Interleukin-16 Protects Nonobese Diabetic Mice From Autoimmune Type 1 Diabetes by a CCL4-Dependent Mechanism

OBJECTIVE: The progressive infiltration of pancreatic islets by lymphocytes is mandatory for development of autoimmune type 1 diabetes. This inflammatory process is mediated by several mediators that are potential therapeutic targets to arrest development of type 1 diabetes. In this study, we invest...

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Detalles Bibliográficos
Autores principales: Meagher, Craig, Beilke, Josh, Arreaza, Guillermo, Mi, Qing-Sheng, Chen, Wei, Salojin, Konstantin, Horst, Noah, Cruikshank, William W., Delovitch, Terry L.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Immunology and Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963545/
https://www.ncbi.nlm.nih.gov/pubmed/20693344
http://dx.doi.org/10.2337/db09-0131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963545/
https://www.ncbi.nlm.nih.gov/pubmed/20693344
http://dx.doi.org/10.2337/db09-0131

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