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Neutralization of Interleukin-16 Protects Nonobese Diabetic Mice From Autoimmune Type 1 Diabetes by a CCL4-Dependent Mechanism
OBJECTIVE: The progressive infiltration of pancreatic islets by lymphocytes is mandatory for development of autoimmune type 1 diabetes. This inflammatory process is mediated by several mediators that are potential therapeutic targets to arrest development of type 1 diabetes. In this study, we invest...
Autores principales: | Meagher, Craig, Beilke, Josh, Arreaza, Guillermo, Mi, Qing-Sheng, Chen, Wei, Salojin, Konstantin, Horst, Noah, Cruikshank, William W., Delovitch, Terry L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963545/ https://www.ncbi.nlm.nih.gov/pubmed/20693344 http://dx.doi.org/10.2337/db09-0131 |
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