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A Systems Biology Approach Identifies Inflammatory Abnormalities Between Mouse Strains Prior to Development of Metabolic Disease

OBJECTIVE: Type 2 diabetes and obesity are increasingly affecting human populations around the world. Our goal was to identify early molecular signatures predicting genetic risk to these metabolic diseases using two strains of mice that differ greatly in disease susceptibility. RESEARCH DESIGN AND M...

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Detalles Bibliográficos
Autores principales: Mori, Marcelo A., Liu, Manway, Bezy, Olivier, Almind, Katrine, Shapiro, Hagit, Kasif, Simon, Kahn, C. Ronald
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963557/
https://www.ncbi.nlm.nih.gov/pubmed/20713682
http://dx.doi.org/10.2337/db10-0367