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E3 Ubiquitin Ligase Synoviolin Is Involved in Liver Fibrogenesis

BACKGROUND AND AIM: Chronic hepatic damage leads to liver fibrosis, which is characterized by the accumulation of collagen-rich extracellular matrix. However, the mechanism by which E3 ubiquitin ligase is involved in collagen synthesis in liver fibrosis is incompletely understood. This study aimed t...

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Detalles Bibliográficos
Autores principales: Hasegawa, Daisuke, Fujii, Ryoji, Yagishita, Naoko, Matsumoto, Nobuyuki, Aratani, Satoko, Izumi, Toshihiko, Azakami, Kazuko, Nakazawa, Minako, Fujita, Hidetoshi, Sato, Tomoo, Araya, Natsumi, Koike, Junki, Tadokoro, Mamoru, Suzuki, Noboru, Nagata, Kazuhiro, Senoo, Haruki, Friedman, Scott L., Nishioka, Kusuki, Yamano, Yoshihisa, Itoh, Fumio, Nakajima, Toshihiro
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963597/
https://www.ncbi.nlm.nih.gov/pubmed/21049091
http://dx.doi.org/10.1371/journal.pone.0013590