When the Optimal Is Not the Best: Parameter Estimation in Complex Biological Models

BACKGROUND: The vast computational resources that became available during the past decade enabled the development and simulation of increasingly complex mathematical models of cancer growth. These models typically involve many free parameters whose determination is a substantial obstacle to model de...

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Detalles Bibliográficos
Autores principales: Fernández Slezak, Diego, Suárez, Cecilia, Cecchi, Guillermo A., Marshall, Guillermo, Stolovitzky, Gustavo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963600/
https://www.ncbi.nlm.nih.gov/pubmed/21049094
http://dx.doi.org/10.1371/journal.pone.0013283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963600/
https://www.ncbi.nlm.nih.gov/pubmed/21049094
http://dx.doi.org/10.1371/journal.pone.0013283

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