Influence of Hsp90 and HDAC Inhibition and Tubulin Acetylation on Perinuclear Protein Aggregation in Human Retinal Pigment Epithelial Cells

Retinal pigment epithelial (RPE) cells are continually exposed to oxidative stress that contributes to protein misfolding, aggregation and functional abnormalities during aging. The protein aggregates formed at the cell periphery are delivered along the microtubulus network by dynein-dependent retro...

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Detalles Bibliográficos
Autores principales: Ryhänen, Tuomas, Viiri, Johanna, Hyttinen, Juha M. T., Uusitalo, Hannu, Salminen, Antero, Kaarniranta, Kai
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963810/
https://www.ncbi.nlm.nih.gov/pubmed/20981255
http://dx.doi.org/10.1155/2011/798052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963810/
https://www.ncbi.nlm.nih.gov/pubmed/20981255
http://dx.doi.org/10.1155/2011/798052

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