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Rapid calcium-dependent activation of Aurora-A kinase

Oncogenic hyperactivation of the mitotic kinase Aurora-A (AurA) in cancer is associated with genomic instability. Increasing evidence indicates that AurA also regulates critical processes in normal interphase cells, but the source of such activity has been obscure. We report here that multiple stimu...

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Detalles Bibliográficos
Autores principales: Plotnikova, Olga V., Pugacheva, Elena N., Dunbrack, Roland L., Golemis, Erica A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963827/
https://www.ncbi.nlm.nih.gov/pubmed/20842194
http://dx.doi.org/10.1038/ncomms1061