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The Structure of the N-Terminus of Kindlin-1: A Domain Important for αIIbβ3 Integrin Activation
The integrin family of heterodimeric cell adhesion molecules exists in both low- and high-affinity states, and integrin activation requires binding of the talin FERM (four-point-one, ezrin, radixin, moesin) domain to membrane-proximal sequences in the β-integrin cytoplasmic domain. However, it has r...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963925/ https://www.ncbi.nlm.nih.gov/pubmed/19804783 http://dx.doi.org/10.1016/j.jmb.2009.09.061 |