The Structure of the N-Terminus of Kindlin-1: A Domain Important for αIIbβ3 Integrin Activation

The integrin family of heterodimeric cell adhesion molecules exists in both low- and high-affinity states, and integrin activation requires binding of the talin FERM (four-point-one, ezrin, radixin, moesin) domain to membrane-proximal sequences in the β-integrin cytoplasmic domain. However, it has r...

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Detalles Bibliográficos
Autores principales: Goult, Benjamin T., Bouaouina, Mohamed, Harburger, David S., Bate, Neil, Patel, Bipin, Anthis, Nicholas J., Campbell, Iain D., Calderwood, David A., Barsukov, Igor L., Roberts, Gordon C., Critchley, David R.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963925/
https://www.ncbi.nlm.nih.gov/pubmed/19804783
http://dx.doi.org/10.1016/j.jmb.2009.09.061

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