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Synthesis, characterization, and biological evaluation of poly(L-γ-glutamyl-glutamine)- paclitaxel nanoconjugate

The purpose of this study was to develop a novel, highly water-soluble poly(L-γ-glutamyl-glutamine)-paclitaxel nanoconjugate (PGG-PTX) that would improve the therapeutic index of paclitaxel (PTX). PGG-PTX is a modification of poly(L-glutamic acid)- paclitaxel conjugate (PGA-PTX) in which an addition...

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Detalles Bibliográficos
Autores principales: Van, Sang, Das, Sanjib K, Wang, Xinghe, Feng, Zhongling, Jin, Yi, Hou, Zheng, Chen, Fu, Pham, Annie, Jiang, Nan, Howell, Stephen B, Yu, Lei
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964040/
https://www.ncbi.nlm.nih.gov/pubmed/21042550
http://dx.doi.org/10.2147/IJN.S13482