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Profiling Y561-Dependent and -Independent Substrates of CSF-1R in Epithelial Cells

Receptor tyrosine kinases (RTKs) activate multiple downstream cytosolic tyrosine kinases following ligand stimulation. SRC family kinases (SFKs), which are recruited to activated RTKs through SH2 domain interactions with RTK autophosphorylation sites, are targets of many subfamilies of RTKs. To date...

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Detalles Bibliográficos
Autores principales: Knowlton, Melodie L., Selfors, Laura M., Wrobel, Carolyn N., Gu, Ting-Lei, Ballif, Bryan A., Gygi, Steven P., Polakiewicz, Roberto, Brugge, Joan S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964295/
https://www.ncbi.nlm.nih.gov/pubmed/21049007
http://dx.doi.org/10.1371/journal.pone.0013587