Intratumoral Convergence of the TCR Repertoires of Effector and Foxp3(+) CD4(+) T cells

The presence of Foxp3(+) regulatory CD4(+) T cells in tumor lesions is considered one of the major causes of ineffective immune response in cancer. It is not clear whether intratumoral T(reg) cells represent T(reg) cells pre-existing in healthy mice, or arise from tumor-specific effector CD4(+) T ce...

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Detalles Bibliográficos
Autores principales: Kuczma, Michal, Kopij, Magdalena, Pawlikowska, Iwona, Wang, Cong-Yi, Rempala, Grzegorz A., Kraj, Piotr
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964305/
https://www.ncbi.nlm.nih.gov/pubmed/21049016
http://dx.doi.org/10.1371/journal.pone.0013623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964305/
https://www.ncbi.nlm.nih.gov/pubmed/21049016
http://dx.doi.org/10.1371/journal.pone.0013623

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