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Age-dependent susceptibility to a viral disease due to decreased natural killer cell numbers and trafficking

Although it is well known that aged hosts are generally more susceptible to viral diseases than the young, specific dysfunctions of the immune system directly responsible for this increased susceptibility have yet to be identified. We show that mice genetically resistant to mousepox (the mouse paral...

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Detalles Bibliográficos
Autores principales: Fang, Min, Roscoe, Felicia, Sigal, Luis J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964566/
https://www.ncbi.nlm.nih.gov/pubmed/20876312
http://dx.doi.org/10.1084/jem.20100282