Cargando…
Age-dependent susceptibility to a viral disease due to decreased natural killer cell numbers and trafficking
Although it is well known that aged hosts are generally more susceptible to viral diseases than the young, specific dysfunctions of the immune system directly responsible for this increased susceptibility have yet to be identified. We show that mice genetically resistant to mousepox (the mouse paral...
Autores principales: | Fang, Min, Roscoe, Felicia, Sigal, Luis J. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964566/ https://www.ncbi.nlm.nih.gov/pubmed/20876312 http://dx.doi.org/10.1084/jem.20100282 |
Ejemplares similares
-
The natural killer cell dysfunction of aged mice is due to the bone marrow stroma and is not restored by IL-15/IL-15Rα treatment
por: Nair, Savita, et al.
Publicado: (2015) -
Natural killer cell distribution and trafficking in human tissues
por: Carrega, Paolo, et al.
Publicado: (2012) -
Direct Presentation Is Sufficient for an Efficient Anti-Viral CD8(+) T Cell Response
por: Xu, Ren-Huan, et al.
Publicado: (2010) -
In Vivo Monitoring of Natural Killer Cell Trafficking During Tumor Immunotherapy
por: Sta Maria, Naomi S, et al.
Publicado: (2014) -
Natural Killer Cells in Viral Hepatitis
por: Rehermann, Barbara
Publicado: (2015)