STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells

Polycomb group (PcG) and trithorax group (TrxG) complexes exert opposing effects on the maintenance of the transcriptional status of the developmentally regulated Hox genes. In this study, we show that activation of STAT6 induces displacement of the PcG complex by the TrxG complex at the upstream re...

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Detalles Bibliográficos
Autores principales: Onodera, Atsushi, Yamashita, Masakatsu, Endo, Yusuke, Kuwahara, Makoto, Tofukuji, Soichi, Hosokawa, Hiroyuki, Kanai, Akinori, Suzuki, Yutaka, Nakayama, Toshinori
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964576/
https://www.ncbi.nlm.nih.gov/pubmed/20956546
http://dx.doi.org/10.1084/jem.20100760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964576/
https://www.ncbi.nlm.nih.gov/pubmed/20956546
http://dx.doi.org/10.1084/jem.20100760

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