Tim3 binding to galectin-9 stimulates antimicrobial immunity

T cell immunoglobulin and mucin domain 3 (Tim3) is a negative regulatory molecule that inhibits effector T(H)1-type responses. Such inhibitory signals prevent unintended tissue inflammation, but can be detrimental if they lead to premature T cell exhaustion. Although the role of Tim3 in autoimmunity...

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Detalles Bibliográficos
Autores principales: Jayaraman, Pushpa, Sada-Ovalle, Isabel, Beladi, Sarah, Anderson, Ana C., Dardalhon, Valerie, Hotta, Chie, Kuchroo, Vijay K., Behar, Samuel M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964580/
https://www.ncbi.nlm.nih.gov/pubmed/20937702
http://dx.doi.org/10.1084/jem.20100687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964580/
https://www.ncbi.nlm.nih.gov/pubmed/20937702
http://dx.doi.org/10.1084/jem.20100687

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