Filamin A regulates focal adhesion disassembly and suppresses breast cancer cell migration and invasion

The actin cross-linking protein filamin A (FLNa) functions as a scaffolding protein and couples cell cytoskeleton to extracellular matrix and integrin receptor signaling. In this study, we report that FLNa suppresses invasion of breast cancer cells and regulates focal adhesion (FA) turnover. Two lar...

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Detalles Bibliográficos
Autores principales: Xu, Yingjie, Bismar, Tarek A., Su, Jie, Xu, Bin, Kristiansen, Glen, Varga, Zsuzsanna, Teng, Lianghong, Ingber, Donald E., Mammoto, Akiko, Kumar, Rakesh, Alaoui-Jamali, Moulay A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964581/
https://www.ncbi.nlm.nih.gov/pubmed/20937704
http://dx.doi.org/10.1084/jem.20100433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964581/
https://www.ncbi.nlm.nih.gov/pubmed/20937704
http://dx.doi.org/10.1084/jem.20100433

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