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Filamin A regulates focal adhesion disassembly and suppresses breast cancer cell migration and invasion
The actin cross-linking protein filamin A (FLNa) functions as a scaffolding protein and couples cell cytoskeleton to extracellular matrix and integrin receptor signaling. In this study, we report that FLNa suppresses invasion of breast cancer cells and regulates focal adhesion (FA) turnover. Two lar...
Autores principales: | Xu, Yingjie, Bismar, Tarek A., Su, Jie, Xu, Bin, Kristiansen, Glen, Varga, Zsuzsanna, Teng, Lianghong, Ingber, Donald E., Mammoto, Akiko, Kumar, Rakesh, Alaoui-Jamali, Moulay A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964581/ https://www.ncbi.nlm.nih.gov/pubmed/20937704 http://dx.doi.org/10.1084/jem.20100433 |
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