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Subtype-associated differences in HIV-1 reverse transcription affect the viral replication

BACKGROUND: The impact of the products of the pol gene, specifically, reverse transcriptase (RT) on HIV-1 replication, evolution, and acquisition of drug resistance has been thoroughly characterized for subtype B. For subtype C, which accounts of almost 60% of HIV cases worldwide, much less is known...

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Detalles Bibliográficos
Autores principales: Iordanskiy, Sergey, Waltke, Mackenzie, Feng, Yanjun, Wood, Charles
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964588/
https://www.ncbi.nlm.nih.gov/pubmed/20939905
http://dx.doi.org/10.1186/1742-4690-7-85