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Subtype-associated differences in HIV-1 reverse transcription affect the viral replication
BACKGROUND: The impact of the products of the pol gene, specifically, reverse transcriptase (RT) on HIV-1 replication, evolution, and acquisition of drug resistance has been thoroughly characterized for subtype B. For subtype C, which accounts of almost 60% of HIV cases worldwide, much less is known...
Autores principales: | Iordanskiy, Sergey, Waltke, Mackenzie, Feng, Yanjun, Wood, Charles |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964588/ https://www.ncbi.nlm.nih.gov/pubmed/20939905 http://dx.doi.org/10.1186/1742-4690-7-85 |
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