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Relative replication capacity of phenotypic SIV variants during primary infections differs with route of inoculation

BACKGROUND: Previous studies of human and simian immunodeficiency virus (HIV and SIV) have demonstrated that adaptive mutations selected during the course of infection alter viral replicative fitness, persistence, and pathogenicity. What is unclear from those studies is the impact of transmission on...

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Detalles Bibliográficos
Autores principales: Biesinger, Tasha, White, Robert, Yu Kimata, Monica T, Wilson, Brenda K, Allan, Jonathan S, Kimata, Jason T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964591/
https://www.ncbi.nlm.nih.gov/pubmed/20942954
http://dx.doi.org/10.1186/1742-4690-7-88