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A structural constraint for functional interaction between N-terminal and C-terminal domains in simian immunodeficiency virus capsid proteins

BACKGROUND: The Gag capsid (CA) is one of the most conserved proteins in highly-diversified human and simian immunodeficiency viruses (HIV and SIV). Understanding the limitations imposed on amino acid sequences in CA could provide valuable information for vaccine immunogen design or anti-HIV drug de...

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Detalles Bibliográficos
Autores principales: Inagaki, Natsuko, Takeuchi, Hiroaki, Yokoyama, Masaru, Sato, Hironori, Ryo, Akihide, Yamamoto, Hiroyuki, Kawada, Miki, Matano, Tetsuro
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964592/
https://www.ncbi.nlm.nih.gov/pubmed/20955553
http://dx.doi.org/10.1186/1742-4690-7-90