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A structural constraint for functional interaction between N-terminal and C-terminal domains in simian immunodeficiency virus capsid proteins
BACKGROUND: The Gag capsid (CA) is one of the most conserved proteins in highly-diversified human and simian immunodeficiency viruses (HIV and SIV). Understanding the limitations imposed on amino acid sequences in CA could provide valuable information for vaccine immunogen design or anti-HIV drug de...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964592/ https://www.ncbi.nlm.nih.gov/pubmed/20955553 http://dx.doi.org/10.1186/1742-4690-7-90 |