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Therapeutic efficacy of alpha-1 antitrypsin augmentation therapy on the loss of lung tissue: an integrated analysis of 2 randomised clinical trials using computed tomography densitometry

BACKGROUND: Two randomised, double-blind, placebo-controlled trials have investigated the efficacy of IV alpha-1 antitrypsin (AAT) augmentation therapy on emphysema progression using CT densitometry. METHODS: Data from these similar trials, a 2-center Danish-Dutch study (n = 54) and the 3-center EXA...

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Detalles Bibliográficos
Autores principales: Stockley, Robert A, Parr, David G, Piitulainen, Eeva, Stolk, Jan, Stoel, Berend C, Dirksen, Asger
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964614/
https://www.ncbi.nlm.nih.gov/pubmed/20920370
http://dx.doi.org/10.1186/1465-9921-11-136