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Macrophages may promote cancer growth via a GM-CSF/HB-EGF paracrine loop that is enhanced by CXCL12

BACKGROUND: Increased numbers of tumour-associated macrophages correlate with shortened survival in some cancers. The molecular bases of this correlation are not thoroughly understood. Events triggered by CXCL12 may play a part, as CXCL12 drives the migration of both CXCR4-positive cancer cells and...

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Detalles Bibliográficos
Autores principales: Rigo, Antonella, Gottardi, Michele, Zamò, Alberto, Mauri, Pierluigi, Bonifacio, Massimiliano, Krampera, Mauro, Damiani, Ernesto, Pizzolo, Giovanni, Vinante, Fabrizio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964621/
https://www.ncbi.nlm.nih.gov/pubmed/20946648
http://dx.doi.org/10.1186/1476-4598-9-273