The apoptotic response in HCT116(BAX-/- )cancer cells becomes rapidly saturated with increasing expression of a GFP-BAX fusion protein

BACKGROUND: Many chemotherapeutic agents promote tumor cell death by activating the intrinsic pathway of apoptosis. Intrinsic apoptosis involves permeabilization of the mitochondrial outer membrane and the release of cytochrome c, a process that is controlled by proteins of the BCL2 gene family. Che...

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Detalles Bibliográficos
Autores principales: Semaan, Sheila J, Nickells, Robert W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964639/
https://www.ncbi.nlm.nih.gov/pubmed/20942963
http://dx.doi.org/10.1186/1471-2407-10-554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964639/
https://www.ncbi.nlm.nih.gov/pubmed/20942963
http://dx.doi.org/10.1186/1471-2407-10-554

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