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Marked potentiation of cell swelling by cytokines in ammonia-sensitized cultured astrocytes

BACKGROUND: Brain edema leading to high intracranial pressure is a lethal complication of acute liver failure (ALF), which is believed to be cytotoxic due to swelling of astrocytes. In addition to the traditional view that elevated levels of blood and brain ammonia are involved in the mechanism of b...

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Detalles Bibliográficos
Autores principales: Rama Rao, Kakulavarapu V, Jayakumar, Arumugam R, Tong, Xiaoying, Alvarez, Veronica M, Norenberg, Michael D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964656/
https://www.ncbi.nlm.nih.gov/pubmed/20942959
http://dx.doi.org/10.1186/1742-2094-7-66