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A mutational analysis and molecular dynamics simulation of quinolone resistance proteins QnrA1 and QnrC from Proteus mirabilis

BACKGROUND: The first report on the transferable, plasmid-mediated quinolone-resistance determinant qnrA1 was in 1998. Since then, qnr alleles have been discovered worldwide in clinical strains of Gram-negative bacilli. Qnr proteins confer quinolone resistance, and belong to the pentapeptide repeat...

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Detalles Bibliográficos
Autores principales:	Guo, Qinglan, Weng, Jingwei, Xu, Xiaogang, Wang, Minghua, Wang, Xiaoying, Ye, Xinyu, Wang, Wenning, Wang, Minggui
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964730/ https://www.ncbi.nlm.nih.gov/pubmed/20932305 http://dx.doi.org/10.1186/1472-6807-10-33

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